SPERM AGGLUTINATION IN THE KEYHOLE LIMPET, MEGATHURA CRENULATA

Wound Hormones of Plants H. the Isolation of a Crystalline Active Substance

abalone sperm appears simply to be concerned in the penetration part of the fertilization process. Summary.-A lytic agent having the property of dissolving the egg membrane has been extracted from sperm of the giant keyhole limpet (Megathura crenulata). The lysin is non-dialyzable and readily inactivated by heat. It precipitates upon saturation of the extract with ammonium sulphate. The precipi...

Extraction of an Egg Membrane-lysin from Sperm of the Giant Keyhole Limpet (mega Thura

Keyhole limpet haemocyanin - a model antigen for human immunotoxicological studies.

Immunization with a T-cell dependent antigen has been promoted as a reliable and sensitive tool for assessing the influence of putative immunotoxic exposures or agents on immune function. Keyhole limpet haemocyanin (KLH) is a very large, copper-containing protein molecule derived from the haemolymph of the inedible mollusc, Megathura crenulata. KLH is a highly immunogenic T-cell dependent antig...

The giant keyhole limpet radular teeth: A naturally-grown harvest machine.

The limpet radula is a feeding organ, which contains more than 100 rows of teeth. During their growth the teeth mature and advance in position along the radula. The simpler doccoglossan radulae operate by grinding rocky substrates, extracting the algae by rasping and scraping with the teeth functioning as shovels. Less is known about the rhipidoglossan radulae, used as rakes or brooms that brus...

Human monoclonal anti-keyhole limpet hemocyanin antibody-secreting hybridoma produced from peripheral blood B lymphocytes of a keyhole limpet hemocyanin-immune individual

A human IgMk monoclonal antibody, 2F7, of predetermined specificity, has been produced by the fusion of human peripheral blood lymphocytes with the nonsecreting mouse myeloma line SP-1. The heterohybridoma has remained stable for over 8 mo, with culture supernatants containing up to 30 micrograms/ml of specific IgM. The antibody has been shown to be capable of inducing a blastogenic response in...